ABSTRACT
To present five patients with VIth nerve palsy and ipsilateral Horner's Syndrome [HS], as a result of cavernous sinus alteration. Consecutive case series. Five patients presented abducens palsy with horizontal diplopia [3 in primary position and 2 in lateral gaze only] and ipsilateral HS. Apraclonidine 0.5% drops evidenced sympathetic denervation in all patients 40-60 min after instillation. All 5 cases had neuroimages [MRI in 3 cases, Computerized Tomography - CT in one case and Magnetic Resonance Angiography - MRA in one case] demonstrating cavernous sinus lesions; 2 meningiomas, 1 carotid-cavernous aneurism, 1 foreign body [bullet] and 1 squamous cell carcinoma. Lesions on the cavernous sinus need to be considered in cases of abducens nerve palsy and ipsilateral Horner's Syndrome